A Promising CPS1 Inhibitor Keeping Ammonia from Fueling Cancer
نویسندگان
چکیده
منابع مشابه
Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid
OBJECTIVE Ammonia detoxification is essential for physiological well-being, and the urea cycle in liver plays a predominant role in ammonia disposal. Nobiletin (NOB), a natural dietary flavonoid, is known to exhibit various physiological efficacies. In the current study, we investigated a potential role of NOB in ammonia control and the underlying cellular mechanism. MATERIALS/METHODS C57BL/6...
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ژورنال
عنوان ژورنال: Cell Chemical Biology
سال: 2020
ISSN: 2451-9456
DOI: 10.1016/j.chembiol.2020.03.002